I think you mean Rathbone Place, which is a tiny side street, a short walk from Tottenham Court Road tube station. From Paddington, take the Bakerloo Line to Oxford Circus and then change to the Central Line for Tottenham Court Road. There are a whole bunch of exits from TCR station - you want Oxford Street north side.
The whole trip, including walking and waiting, shouldn't take more than about 25 minutes. A cab from Paddington may be quicker, but you stand a fair chance of spending a long time waiting in line and then another long wait, this time with the meter running, stuck in traffic in Oxford Street.
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