Maine is beautiful. I really love Maine. But, you could go to New York City. It's crowded but there's just so much life. You could also go to Los Angeles in California and go to Disneyland. :D
It depends on where you're coming from and where you're going to. If both locations are close to the border, drive. If they are really far apart, then fly.
do you mean what airline? If so- it depends are where are leaving from and flying too. Both are huge countries...with this vague question the only answer I can offer you is to look at expedia.com or a simular website....travelocity.com
Good luck
stop in Niagara Falls/Buffalo, New York, gateway to Canada. Its definitely an All-America city with great food, nightlife, modern art, zoo, science museum, beautiful parks, architecture and history, etc.