Is there a site that assist in planning a family vacation via road travel?

My husband and nine year old daughter would like to travel from Ohio down to Florida. Stopping at all desirable locations in between. Perhaps renting a condo, or vacation home rental in North or South Carolina for several days. Does anyone have any suggestions? Help please. Thank you to everyone that read my question and also to anyone that provides suggestions.

If they come down I-26 there is a Town called Hendersonville it is a small mountain town ,old fashion main street side walk cafes
and a lot of Antique stores and shops there . they have rental cottages there... there are also log cabin rentals as well ..if that is there thing... off of 26 in SC there is nothing much in Spartanburg SC ..Seems like if they like the Big city style they would drive through Atlanta Ga. to Fla. if they are going to ride the Coast line there are places all the way from the Crystal beaches in NC through Myrtle beach , down through Charleston , etc.. Savanna Ga. is nice too go to each state website and check it out , if you have broad band download google earth you can zoom in almost street level to most populated areas ... and look around for the type of environment or surroundings you are looking for
It depends on the route they are going to be taking ..

This site is very good for planning a road trip. It allows for multiple stops.
Indicates mileage, gives directions and maps.
At each place you stop, hotel links are supplied.
http://www.randmcnally.com/

You first need to decide on your route.
Ohio is quite a large state and I'm not sure where your setting out from (I guess you might travel I77; following the Ohio River south is quite pleasant and Wheeling is a very nice city).

Do a net search for accommodation in the areas that interest you.
The best suggestion I can offer you is to buy yourself a Rand McNally (book-size) road atlas.
They have scenic routes and attractions marked.