Not possible. Tourist visas cannot be converted into any form of temporary residence or immigration visa. Just applying for change of status is prima facie evidence of immigration fraud on the tourist visa application. $10,000 fine and permanent bar to getting any future visa.
She has no choice but to go home for at least 6-12 months, then see if she qualifies to get a job in a category for a temporary employment visa. She'll need at least a college degree and 2 years post-baccalaureate experience to apply for a work visa. The job market is very bad, so unless she has special skills, there isn't much hope of a work visa for at least the next 12 months any way.
If she wants to immigrate and get a green card, she has to apply in her home country. And she has to have a sponsor who is an immediate blood relative (not a cousin). If she is accepted, she will have to wait until her priority number comes up. It will take several years and she cannot enter the US until she gets permission to enter on the immigration visa.
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